ION Channel Program > Publications

2015
TRPC3 channels critically regulate hippocampal excitability and contextual fear memory
(Neuner, Wilmott, Hope, Hoffmann, Chong, Abramowitz, Birnbaumer, O'Connell, Tryba, Greene, Savio Chan, Kaczorowski: Behavioural Brain Research)

2014
TRPV4 mediates myofibroblast differentiation and pulmonary fibrosis in mice
(Rahaman, Grove, Paruchuri, Southern, Abraham, Niese, Scheraga, Ghosh, Thodeti, Zhang, Moran, Schilling, Tschumperlin, Olman: Journal of Clinical Investigation)

2012
Transient receptor potential ankyrin 1 as a target for perioperative pain management
(Moran: Anesthesiology)

2011
Transient receptor potential channels as therapeutic targets
(Moran, McAlexander, Biros, Szallasi: Nature Reviews Drug Discovery, USA)

2010
TRPping up overactive bladder
(Cain: Science-Business eXchange, USA)

TRPA1 Contributes to Cold Hypersensitivity
(del Camino, Murphy, Heiry, Barrett, Earley, Cook, Petrus, Zhao, D’Amours, Deering, Brenner, Costigan, Hayward, Chong, Fanger, Woolf, Patapoutian, Moran: The Journal of Neuroscience, USA)

Inhibition of the cation channel TRPV4 improves bladder function in mice and rats with cyclophosphamide-induced cystitis
(Everaerts, Zhen, Ghosh, Vriens, Gevaert, Gilbert, Hayward, McNamara, Xue, Moran, Strassmaier, Uykal, Owsianik, Vennekens, De Ridder, Nilius, Fanger, Voets: The Proceedings of the National Academy of Sciences, USA)

2009
A sensory neuronal ion channel essential for airway inflammation and hyperreactivity in asthma
(Caceres, Brackmann, Elia, Bessac, del Camino, D'Amours, Witek, Fanger, Chong, Hayward, Homer, Cohn, Huang, Moran, Jordt: Proc Nat Acad Sci, USA)

Pharmacological blockade of TRPA1 inhibits mechanical firing in nociceptors
(Kerstein, del Camino, Moran, Stucky: Molecular Pain)

Essential Role for TRPC5 in Amygdala Function and Fear-Related Behavior
(Riccio, Li, Moon, Kim, Smith, Rudolph, Gapon, Yao, Tsvetkov, Rodig, Van't Veer, Meloni, Carlezon, Bolshakov, Clapham: Cell)

2008
Transient receptor potential ankyrin 1 antagonists block the noxious effects of toxic industrial isocyanates and tear gases
(Bessac, Sivula, von Hehn, Caceres, Escalera, Jordt: FASEB Journal)

2007
TRPA1 mediates formalin-induced pain
(McNamara, Mandel-Brehm, Bautista, Siemens, Deranian, Zhao, Hayward, Chong, Julius, Moran, Fanger: Proc Nat Acad Sci, USA)

2006
Nomenclature and structure-function relationships of transient receptor potential channels
(Clapham, Julius, Montell, Schultz: Pharm Rev)

An Introduction to TRP Channels
(Ramsey, Delling, Clapham: Annual Reviews of Physiology)

2005
Camphor Activates and Strongly Desensitizes the Transient Receptor Potential Vanilloid Subtype 1 Channel in a Vanilloid-Independent Mechanism
(Zu, Blair, Clapham; Journal of Neuroscience)

Nomenclature and structure-function relationships of CatSper and Two-Pore Channels
(Clapham, Garbers: Pharmacol Rev)

TRP channels and mice deficient in TRP channels
(Desai, Clapham: Pflugers Arch)

2004
Phosphatidylinositol 3-kinase activates ERK in primary sensory neurons and mediates inflammatory heat hyperalgesia through TRPV1 sensitization
(Zhuang, Clapham, Ji: J Neurosci)

An intronic mutation causes long QT syndrome
(Zhang, Vincent, Baralle M, Baralle FD, Anson, Benson, Whiting, Timothy, Carlquist, January, Keating, Splawski: J Am Coll Cardiol)

Rapid vesicular translocation and insertion of TRP channels
(Bezzerides, Ramsey, Kotecha, Greka, Clapham: Nat Cell Biol)

TRP ion channels in the nervous system
(Moran, Clapham: Curr Opin Neurobiol)

2003
CatSper1 required for evoked Ca2+ entry and control of flagellar function in sperm
(Carlson, Westenbroek, Quill, Ren, Clapham, Hille, Garbers, Babcock)

TRP Channels as Cellular Sensors
(Clapham. Nature, Volume 426.)

2001
A Voltage-gated Ion Channel Expressed Specifically in Spermatozoa
(Quill, Ren, Clapham, Garbers: PNAS, Volume 98.)

A Sperm Ion Channel Required for Sperm Motility and Male Fertility
(Ren, Navarro, Clapham et al. Nature, Volume 413.)

The TRP Ion Channel Family
(Clapham, Runnels, Strubing. Nature Reviews Neuroscience, Volume 2.)